In many vertebrates, the enzymatic oxidation of dietary yellow carotenoids generates red keto‐carotenoids giving color to ornaments. The oxidase CYP2J19 is here a key effector. Its purported intracellular location suggests a shared biochemical pathway between trait expression and cell functioning. This might guarantee the reliability of red colorations as individual quality signals independent of production costs. We hypothesize that the ornament type (feathers vs. bare parts) and production costs (probably CYP2J19 activity compromising vital functions) could have promoted tissue‐specific gene relocation. (...) We review current avian tissue‐specific CYP2J19 expression data. Among the ten red‐billed species showing CYP2J19 bill expression, only one showed strong hepatic expression. Moreover, a phylogenetically‐controlled analysis of 25 red‐colored species shows that those producing red bare parts are less likely to have strong hepatic CYP2J19 expression than species with only red plumages. Thus, both production costs and shared pathways might have contributed to the evolution of red signals. (shrink)

Assessing physical fitness has emerged as a proxy of the health status of children and adolescents and therefore as relevant from a public health point of view. DAFIS is a project included in Plan Galicia Saudable of the regional government of Galicia. DAFIS consists of an on-line software devoted to record the results of a standard physical fitness protocol carried out as a part of the physical education curriculum. The aims of this study were: to obtain normative values of physical (...) fitness of the Galician school population evaluated in the DAFIS project, and to identify a reduced number of components and tests able to capture a significant amount of the variability in the physical fitness of children and adolescents. From an initial sample of 27784 records, 15287 cases were considered after filtering. Generalized Additive Models for Location, Scale and Shape were used for obtaining percentile curves and tables for each sex. Furthermore, a principal components analysis was performed, selecting the number of components by applying the Kaiser’s rule and selecting a subset of variables considering the correlation between each variable and the components. Percentile curves and normative values are reported for each test and sex. Physical fitness was better in boys than in girls throughout age groups, except for flexibility that was consistently higher in girls. Two main components were detected throughout age groups: the first one representing body composition and partially cardiorespiratory fitness and the second one muscular fitness. For boys and girls, waist to height ratio had the highest correlations with the first component in four out of six age groups. The highest correlation with the second component, was most frequently observed for the handgrip test both in boys and girls. This study provides evidence about the utility of school community actions like DAFIS aimed to track the health-related fitness of children and adolescents. The results suggest that fat mass distribution and muscular performance concentrate a high proportion physical fitness variance. (shrink)

Cognitive symptoms after COVID-19 have been increasingly recognized several months after the acute infection and have been designated as “brain fog.” We report a patient with cognitive symptoms that started immediately after COVID-19, in which cerebrospinal fluid biomarkers were highly suggestive of Alzheimer’s disease. Our case highlights the need to examine patients with cognitive symptoms following COVID-19 comprehensively. A detailed assessment combining clinical, cognitive, and biomarker studies may help disentangle the underlying mechanisms associated with cognitive dysfunction in each case. The (...) investigation of neurodegenerative processes in an early stage, especially in older patients, is probably warranted. (shrink)

Esta entrevista se realizó en dos sesiones vía Zoom, cuyas fechas están ubicadas en agosto de 2021. La primera conversación que se tuvo consistió en que el filósofo Modesto Gómez Alonso brindara unas ideas panorámicas y reflexivas, las cuales se han colocado al inicio de cada resolución. Entretanto, en la segunda conversación, se partió de lo planteado anteriormente y de algunos apuntes que permitieron esbozar de una forma más contundente las respuestas. Todo este procedimiento sirvió para que se pudiera (...) tratar sobre la noción de la epistemología desde sus múltiples manifestaciones. Es por eso por lo que el filósofo Modesto Gómez recurrió a concepciones afines, como aquellas que proporcionan el conocimiento, al igual que buscó explicar con mayor detalle al citar a autores como Descartes, Sosa, entre otros. En ese sentido, esta entrevista tuvo el propósito de buscar las conexiones que existen de la Filosofía con la vida cotidiana en cuanto a que se indaga de las posibilidades de contribuir al conocimiento y contar con las herramientas adecuadas. (shrink)

Class, race and gender are three of the most salient factors in society. They determine to an important extent the opportunities we have, e.g. to access public.

In this work I consider two arguments for the conclusion that nonhuman animals are not owed justice. Some argue that justice is solely a matter of distributing material goods and that this excludes nonhuman animals from the sphere of justice. This argument fails for two reasons. First, even if it's true that justice is solely a matter of distributing material goods, it's not clear that it follows that nonhuman animals are not owed justice. Second, the claim that justice is solely (...) a matter of distributing material goods is false. Some argue that the recipients of justice can be determined by some contractarian theory--and that contractarian theories exclude nonhuman animals. Against this, I note that many contractarian theories have implausible consequences and that the most plausible forms of contractarianism don't exclude nonhuman animals. I then explore briefly what including nonhuman animals in the sphere of justice would look like. (shrink)

When reasoning about dependence relations, philosophers often rely on gradualist assumptions, according to which abrupt changes in a phenomenon of interest can result only from abrupt changes in the low-level phenomena on which it depends. These assumptions, while strictly correct if the dependence relation in question can be expressed by continuous dynamical equations, should be handled with care: very often the descriptively relevant property of a dynamical system connecting high- and low-level phenomena is not its instantaneous behaviour but its stable (...) fixed points (those in the vicinity of which it spends most of the time, after comparatively short transitory periods), and stable fixed points can change abruptly as a result of infinitesimal changes of the low-level phenomenon. We illustrate this potential gradualist trap by showing that Chalmers’ fading qualia argument falls into it. (shrink)

A presente obra trata, de forma inigualável, das preliminares ao estudo da teoria tridimensional do direito, examinando a Filosofia e a Ciência do Direito, as dimensões da experiência jurídica, a posição do tridimensionalismo jurídico concreto, a dialética de complementaridade, o personalismo e o historicismo axiológico, as estruturas e os modelos do Direito no processo cultural e a visão integral do mundo jurídico.

This comic, serious inquiry into the nature of art takes its technical vocabulary from Alice’s Adventures in Wonderland and Through the Looking-Glass. It is ridiculous to think of poems, paintings, or films as distinct from other things in the world, including people. Talking about art should be contiguous with talking about other relevant matters.

pt. 1. The form of the state : on beginnings -- pt. 2. Machiavelli's theory of history : modes of encounter between action and time -- pt. 3. The event of the republic : the return to beginnings.

Em analogia com outras discriminações, como o racismo ou o sexismo, o especismo é concebido como uma forma de discriminação moral com base na espécie. Em grande medida, a discussão contemporânea sobre a importância moral dos animais surgiu e desenvolveu-se em torno da crítica e da defesa do especismo. Este artigo oferece uma visão da discussão filosófica contemporânea sobre o especismo. Após uma breve introdução, apresenta-se uma definição de especismo e caracterizam-se vários tipos de especismo, sendo o Antropocentrismo o mais (...) relevante. Depois, expõe-se um argumento proeminente contra o Antropocentrismo: o argumento dos casos marginais. Por fim, algumas posições antropocêntricas são criticamente discutidas. (shrink)

v. 1. Propedêutica filosófia. v. 2. Ontognoseologia juridica.

The transformative power of artificial intelligence (AI) is coming to philosophy—the only question is the degree to which philosophers will harness it. In this paper, we argue that the application of AI tools to philosophy could have an impact on the field comparable to the advent of writing, and that it is likely that philosophical progress will significantly increase as a consequence of AI. The role of philosophers in this story is not merely to use AI but also to help (...) develop it and theorize about it. In fact, we argue that philosophers have a prima facie obligation to spend significant effort in doing so, at least insofar as they should spend effort philosophizing. (shrink)

A strikingly original work, Friends of Interpretable Objects re-anchors aesthetics in the object of attention even as it redefines the practice, processes, ...

Explaining agency is a significant challenge for those who are interested in the sciences of the mind, and non-representationalists are no exception to this. Even though both ecological psychologists and enactivists agree that agency is to be explained by focusing on the relation between the organism and the environment, they have approached it by focusing on different aspects of the organism-environment relation. In this paper, I offer a suggestion for a radical embodied account of agency that combines ecological psychology with (...) recent trends in enactive cognitive science. According to this proposal, while enactivism focuses primarily on describing how our acquired sensorimotor schemes and habits mutually equilibrate, affecting our tendency to act upon some affordances instead of others, ecological psychology focuses on studying how perceptual information contributes to the actualization of the sensorimotor schemes and habits without mediating representations, inferences, and computations. The paper concludes by briefly exploring how this ecological-enactive theory of agency can account for how socio-cultural norms shape human agency. (shrink)

Miembro de la generaci n de el Viejo Topo, Morey se ha formado en el rigor de la filosof a, de la que es catedr tico en la Universidad de Barcelona. el presente libro es una novela de corte experimental acerca de la errancia y el peregrinaje sin destino a que nos somete la paradoja de vivir o ser vividos.

Representations are not only used in our folk-psychological explanations of behaviour, but are also fruitfully postulated, for example, in cognitive science. The mainstream view in cognitive science maintains that our mind is a representational system. This popular view requires an understanding of the nature of the entities they are postulating. Teleosemantic theories face this challenge, unpacking the normativity in the relation of representation by appealing to the teleological function of the representing state. It has been argued that, if intentionality is (...) to be explained in teleological terms, then the function of a state cannot depend on its phylogenetical history, given the metaphysical possibility of a duplicate of an intentional being that lacks an evolutionary history. In this paper, I present a method to produce, according to our current knowledge in genetic engineering, human-like individuals who are not the product of natural selection in the required sense. This variation will be used to shed light on the main replies that have been offered in the literature to the Swampman thought experiment. I argue that these replies are not satisfactory: representations should better not depend on natural selection. I conclude that a non-etiological notion of function is to be preferred for characterizing the relation of representation. (shrink)

En Los Cuatro Acuerdos, un éxito de ventas en todo el mundo, don Miguel Ruiz revelaba cómo el proceso de educación, o «domesticación», nos hace olvidar nuestra sabiduría innata. A lo largo de la vida establecemos muchos acuerdos que van en nuestra contra y nos causan un sufrimiento innecesario. Los Cuatro Acuerdos nos ayudan a romper estos acuerdos limitadores y a substituirlos por otros que nos aportan libertad, felicidad y amor. Ahora don Miguel Ruiz, junto con su hijo (...) don Jose Ruiz, nos ofrece una nueva perspectiva de Los Cuatro Acuerdos y un acuerdo nuevo y poderoso para transformar nuestra vida en nuestro cielo personal: el quinto acuerdo. El Quinto Acuerdo nos permite adquirir una conciencia más profunda del poder del yo verdadero y recuperar la autenticidad con la que nacimos. En esta absorbente continuación del libro que ha cambiado la vida de millones de personas de todo el mundo, se nos recuerda el mejor regalo que podemos hacernos: la libertad de ser quienes realmente somos. Más sobre el libro Imagínate llevando una vida totalmente nueva: una vida en la que eres libre de ser quien realmente eres. Ya no te riges por lo que los demás piensan de ti. Imagínate viviendo sin juzgarte a ti mismo ni juzgar a los demás, sin temer ser juzgado. Te aceptas tal como eres y aceptas a los demás tal como son. Imagínate viviendo sin estar en conflicto contigo ni con la gente. Te respetas a ti mismo y a los demás, y a cambio ellos te respetan a ti. Imagínate viviendo sin miedo a expresarte ni a explorar la vida. Vives sin temor, sin culparte, sin avergonzarte, sin arrepentirte. Imagínate que te encanta ser como eres. Te gusta tu cuerpo tal como es, te gustan tus emociones tal como son. Imagínate siendo tú mismo. Eres feliz y disfrutas verdaderamente de tu vida. ¡Imagínate viviendo con esta clase de libertad personal! Esta manera de vivir es completamente posible. Otros lo han conseguido y tú también lo harás. Sólo necesitas hacer de los Cinco Acuerdos tu estilo de vida y pronto vivirás tu sueño personal del cielo. (shrink)

The traditional approach in cognitive sciences holds that cognition is a matter of manipulating abstract symbols followingcertain rules. According to this view, the body is merely an input/output device, which allows the computationalsystem—the brain—to acquire new input data by means of the senses and to act in the environment following its com-mands. In opposition to this classical view, defenders of embodied cognition (EC) stress the relevance of the body inwhich the cognitive agent is embedded in their explanation of cognitive processes. (...) From a representationalist frameworkregarding our conscious experience, in this article, I will offer a novel argument in favor of EC and show that cognitionconstitutively—and no merely causally—depends upon body activity beyond that in the brain. In particular, I will arguethat in order to solve the problem derived from the empirical evidence in favor of the possibility of shifted spectrum,representationalist should endorse the view that experiences concern its subject: the content of experience isde se.Ishow that this claim perfectly matches the phenomenological observation and helps explaining the subjective characterof the experience. Furthermore, I argue that entertaining this kind of representation constitutively depends on bodilyactivity. Consequently, insofar as cognition depends on consciousness, it is embodied. (shrink)

Presents advice on how to gain personal freedom by following the wisdom of the Toltecs.

El presente trabajo investiga las tesis sobre el poder civil de Alonso de la Veracruz que buscan incorporar en la comunidad política española a los habitantes autóctonos del Nuevo Mundo, tesis que suelen relacionarse con F. de Vitoria y el tomismo español, y que últimamente son consideradas parte del republicanismo novohispano elaborado desde la periferia americana. Se busca demostrar que su propósito era aplicar una teoría de derechos naturales, sin que ello implique participación política de los indios americanos. Se (...) analiza la postura del fraile frente a la diversidad cultural y la guerra contra los indios. The paper explores Alonso de la Veracruz's theses on civil power, which sought to integrate the native inhabitants of the New World into the Spanish political community. These theses, which have usually been associated with F. de Vitoria and Spanish Thomism, have recently come to be considered part of a Novohispanic republicanism developed in the American periphery. The article seeks to show that the purpose of such theses was to apply a theory of natural rights that did not entail the political participation of the indigenous population, as well as to analyze Veracruz's position regarding cultural diversity and the war against the indigenous peoples. (shrink)

The well-known distinction between access consciousness and phenomenal consciousness has moved away from the conceptual domain into the empirical one, and the debate now is focused on whether the neural mechanisms of cognitive access are constitutive of the neural correlate of phenomenal consciousness. In this paper, I want to analyze the consequences that a negative reply to this question has for the cognitive phenomenology thesis – roughly the claim that there is a “proprietary” phenomenology of thoughts. If the mechanisms responsible (...) for cognitive access can be disentangled from the mechanisms that give rise to phenomenology in the case of perception and emotion, then the same disentanglement is to be expected in the case of thoughts. This, in turn, presents, as I argue, a challenge to the cognitive phenomenology thesis: either there are thoughts with cognitive phenomenology we lack cognitive access to or there are good reasons to doubt that there is such a thing as cognitive phenomenology. I discuss a... (shrink)

Despite the emergence of computer games as a dominant cultural industry, we know little or nothing about the ethics of computer games. Considerations of the morality of computer games seldom go beyond intermittent portrayals of them in the mass media as training devices for teenage serial killers. In this first scholarly exploration of the subject, Miguel Sicart addresses broader issues about the ethics of games, the ethics of playing the games, and the ethical responsibilities of game designers. He argues (...) that computer games are ethical objects, that computer game players are ethical agents, and that the ethics of computer games should be seen as a complex network of responsibilities and moral duties. Players should not be considered passive amoral creatures; they reflect, relate, and create with ethical minds. The games they play are ethical systems, with rules that create gameworlds with values at play. Drawing on concepts from philosophy and game studies, Sicart proposes a framework for analyzing the ethics of computer games as both designed objects and player experiences. After presenting his core theoretical arguments and offering a general theory for understanding computer game ethics, Sicart offers case studies examining single-player games, multiplayer games, and online gameworlds from an ethical perspective. He explores issues raised by unethical content in computer games and its possible effect on players and offers a synthesis of design theory and ethics that could be used as both analytical tool and inspiration in the creation of ethical gameplay. (shrink)